中华皮肤科杂志 ›› 2009, Vol. 42 ›› Issue (10): 671-673.

• 论著 • 上一篇    下一篇

浅表肢端纤维黏液瘤一例

尹志强1,张美华2,周芳3,等4   

  1. 1. 南京医科大学第一附属医院皮肤性病科
    2. 南京医科大学第一附属医院皮肤科
    3. 南京医科大学第一附属医院整形烧伤科
    4.
  • 收稿日期:2008-10-21 修回日期:2008-10-29 发布日期:2009-10-09
  • 通讯作者: 尹志强 E-mail:yzq2802@sina.com
  • 基金资助:

    无

Superficial acral fibromyxoma: a case report

  • Received:2008-10-21 Revised:2008-10-29 Published:2009-10-09

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摘要：

患者男，43岁，左足跟肿块7年余。无明显不适，行走时偶尔有疼痛，逐渐增大。临床表现为左足跟1.5 cm × 1.5 cm大小浅红色、质硬、境界清楚的肿块。病理检查可见黏液样基质中较多的梭形或星形细胞增殖呈席纹样或束状排列，其间可见有较多的小血管，梭形或星形细胞未见明显异形。免疫组化显示波形蛋白、纤维结合素、CD34和上皮膜抗原阳性，平滑肌抗体、S-100、神经微丝、结蛋白和CD99均为阴性。诊断为浅表肢端纤维黏液瘤。行足跟部肿块扩大切除术合并游离皮片移植术，术后随访5月余未见复发。

关键词: 肢端, 纤维粘液瘤, 足跟, 浅表

Abstract:

A case of superficial acral fibromyxoma is reported. A 43-year-old male patient presented with a 7-year-history progressive mass arising on the left heel. There was no evident discomfort but occasional pain during walking. Clinical examination revealed a plum, solid, well-defined mass sized 1.5 cm × 1.5 cm on the left heel. Histologically, there was a proliferation of numerous spindle or stellate cells arranged in a storiform or fascicular pattern embedded in a myxoid stroma with many small blood vessels; no evident atypia or mitosis was observed in these cells. Immunohistochemical staining of lesional tissue was positive for vimentin, fibronectin, CD34 and early membrane antigen, but negative for smooth muscle antibody, S-100, neurofilaments, desmin or CD99. A diagnosis of superficial acral fibromyxoma was made. The tumor was removed by expanded excision followed by free skin flap transplantation. No recurrence was observed during a 5-month follow up.