中华皮肤科杂志

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强脉冲光治疗面部皮肤老化的观察

吴严1, 李远宏1, 刘梅1, 董光辉2, 张丽1, 舒春梅3, 高兴华1, 何春涤1, 陈洪铎1   

  1. 1. 中国医科大学附属第一医院皮肤科, 沈阳, 110001;
    2. 中国医科大学公共卫生学院卫生统计教研室;
    3. 滨州医学院附属医院皮肤科
  • 收稿日期:2006-08-25 出版日期:2007-07-15 发布日期:2007-07-15
  • 通讯作者: 陈洪铎,email:chenhd@cae.cn E-mail:chenhd@cae.cn

Intense pulse light in the treatment of facial aging

WU Yan1, LI Yuan-hong1, LIU Mei1, DONG Guang-hui2, ZHANG Li1, SHU Chun-mei3, GAO Xing-hua1, HE Chun-di1, CHEN Hong-duo1   

  1. Department of Dermatology, No.1 Hospital of China Medical University, Shenyang 110001, China
  • Received:2006-08-25 Online:2007-07-15 Published:2007-07-15

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摘要： 目的 观察强脉冲光治疗面部皮肤老化如不规则色素改变、毛细血管扩张、皮肤干燥、粗糙、细皱纹的临床疗效.方法 用强脉冲光治疗178例面部皮肤老化患者,共进行4次治疗,每次间隔3～4周.治疗前后医生对患者面部皮肤进行整体评分,测定皮肤黑素指数、红斑指数和角质层含水量、治疗结束后1个月进行患者满意度自评.结果 治疗后医生主观评分改变显著,患者满意率为90.45%;第4次治疗后黑素指数和红斑指数下降最明显,其次为第1次治疗后.治疗对角质层含水量影响不显著.结论 强脉冲光可安全高效地治疗面部皮肤老化.

关键词: 皮肤衰老, 强脉冲光, 黑素指数, 红斑指数

Abstract: Objective To evaluate the efficacy of intense pulse light(IPL)in the treatment of facial aging,including unevenness in pigmentation,telangiectasis,skin dryness,roughness and fine wrinkles. Methods One hundred and seventy-eight patients with facial aging were treated with IPL for four times at an interval of 3-4 weeks.Assessment of global aging scores was performed for these patients by doctors betbre and one month after the final treatment.Patients' satisfaction was also investigated one month after the final treatment.Skin melanin index,erythema index and water content of stratum corneum were tested before and one month after the final treatment.Results One month after the final treatment,the global aging scores assessed by doctors significantly decreased in comparison with the baseline scores before treatment,and the patients' satisfaction rate reached 90.45%;the melanin index was significantly reduced on the forehead,pcriorbital region,perioral region and lower mandible(all P<0.01);and erythema index significantly fell on the forehead(P<0.01),around the lips(P<0.05),and on the lower mandible(P<0.05).No statistical changes were observed for the water content of stratum corneum before and after the treatment,Conclusion IPL is a safe and highly effective treatment option for facial aging.

Key words: Skin aging, Intense pulsed light, Melanin index, Erythema index