中华皮肤科杂志 ›› 1998, Vol. 31 ›› Issue (6): 348-350.

• 论著 • 上一篇    下一篇

冻土毛霉所致的原发性皮肤毛霉病

王俊杰1, 廖元兴1, 徐德兴2, 王露霞2, 赖日权3   

  1. 1. 广州军区广州总医院皮肤科, 广州 510010;
    2. 广州军区广州总医院检验科, 广州 510010;
    3. 广州军区广州总医院病理科, 广州 510010
  • 收稿日期:1998-05-07 修回日期:1998-07-14 出版日期:1998-12-15 发布日期:1998-12-15

Primary Cutaneous Mucormycosis Caused by Mucor Hiemalis F.Luteus

Yuanxing1, Xu Dexing1   

  1. Department of Dermatology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010
  • Received:1998-05-07 Revised:1998-07-14 Online:1998-12-15 Published:1998-12-15

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摘要： 目的 报道一例罕见的由冻上毛霉黄色(或上黄)变种所致的原发性皮肤毛霉病.方法 取患者面部焦痂下脓性分泌物直接镜检及培养, 取面部活检组织部分行组织病理, 部分做真菌培养 结果 直接镜检可见粗的、无分隔的、成直角分支的菌丝, 活检组织切片, HE染色示:肉芽肿样改变, 并可见特征性的、宽的、无分隔的菌丝、PAS(+);脓性分泌物及活检部分组织25℃SDA培养3天后, 可见黄色的菌落, 37℃不生长、菌种鉴定为:冻土毛毒黄色(或上黄)变种经口服伊曲康唑胶囊治愈.

关键词: 毛霉菌病, 毛霉菌属

Abstract: Objective Wereport a rare ease of primarv cutaneous mucormvcosis, caused by muc hiemalisf.lulens(Linnemann)schipper.Methods (1)VIcrsexamination, of KOH preparation and culof purulent seeretion under the eachar from the face.(2)bionsy frome skin lesion was also, taken for pathologic examinattion, and culture.Results and Conclusion(I)Mieromseopicamination showed characteristic thick, nonseplate right-angled branched hyphae.(2)H.E stain of biopsy specimen reveled granulomatous change and characleristic broad, nonseplate hyphae which was PAS(+).(3)Yellow colonies were observed, on the culurs, of purulent secrelion and biopay specinmen with SDA media at 25℃ for 3 days. but no growth at 37℃.and the fugus was identilied as M. hiemulisf. luteus(linnemunn)Schipper. Treatment, of the patient with sporano(ltraconazole)was successful.

Key words: Mueormveosis, Mueor