中华皮肤科杂志 ›› 1997, Vol. 30 ›› Issue (4): 227-229.

• 论著 • 上一篇    下一篇

系统性红斑狼疮神经精神损害患者的磁共振/计算机X线断层照相术分析

郭庆1, 李国照2, 许德清1   

  1. 1. 中山医科大学孙逸仙纪念医院皮肤科, 广州 510120;
    2. 中山医科大学孙逸仙纪念医院MR/CT室, 广州 510120
  • 收稿日期:1996-07-02 修回日期:1996-11-01 出版日期:1997-08-15 发布日期:1997-08-15

MR/CT Analyses of the Neuropsychiatric Disorders in Patients with Systemic Lupus Erythematosis

Guo Qing1, Li Guozhao2, Xu Deqing1   

  1. Department of Dermatology, MR/CT Room, Memorial Hospital of Sun Yat-Sen University of Medical Sciences, Guang Zhou 510120
  • Received:1996-07-02 Revised:1996-11-01 Online:1997-08-15 Published:1997-08-15

摘要: 为了探讨磁共振/计算机X线断层照相术(MR/CT)检查对系统性红斑狼疮神经精神损害(SLE-NP)的诊断、鉴别诊断、治疗和预后的价值,分析了16例SLE-NP患者22例次MR/CT检查的图象变化的临床意义。16例SLE-NP患者共进行了22例次头颅或脊髓MR/CT检查,其结果示:图象异常18例次(占81.8%).缺血/梗塞9例次,出血3例次,局限性脱髓鞘3例次,脑萎缩6例次。病变部位在基底节区10例次,侧脑室前角5例次,桥脑1例次,脊髓2例次。MR/CT检查对SLE-NP敏感,总阳性率达81.8%,其高分辨率显示的损害性质和部位,对SLE-NP的早期诊断、鉴别诊断、指导治疗、评价疗效和预后均能提供有参考价值的依据。

关键词: 红斑狼疮, 系统性, 神经精神损害, 磁共振/计算机X线断层照相术

Abstract: In order to study the values of MR/CT to the diagnosis, differential diagnosis, treatment and prognosis of systemic lupus erythematosis with neuropsyehiatric disorders (SLE-NP), MR/CT image changes of 22 examinations of skull/spinal cord in 16 patients with SLE-NP were analyzed. The results showed that the images of 18 examinations were abnormal (81.8%), including ischaemia/infarct (9 times), haemorrhage (3 times), focal demyelination (3 times), and cerebral atropy (6 times). The areas involved including basal ganglia (10 times), anterior horn of lateral ventricle (5 times), pons (1 time), and spinal cord (2 times). MR/CT is sensitive for the examination of lesions of SLE-NP, and the total positive rate is as high as 81.8%. Its high resolution rate can display the nature and areas of the lesions, which may provide valuable reference for the early diagnosis, differential diagnosis, treatment, evaluation of therapeutic efficacy and prognosis of SLE-NP.

Key words: Lupus erythmatosus, systemic, Neuropsychosis, Magnetic resonance/Computed tomography