中华皮肤科杂志 ›› 1997, Vol. 30 ›› Issue (3): 175-177.

• 论著 • 上一篇    下一篇

CO2激光治疗尖锐湿疣烟尘中HPVDNA的检测

顾恒, 常宝珠, 陈崑, 张树文, 曹宁校, 陈琴芳, 郑志菊, 张小华, 邵长庚, 李光中   

  1. 中国医学科学院、中国协和医科大学皮肤病研究所, 南京210042
  • 收稿日期:1996-12-09 修回日期:1997-01-30 出版日期:1997-06-15 发布日期:1997-06-15

Detection of HPV DNA in the Vapor During Carbon Dioxide Laser Treatment of Condyloma Acuminatum

Gu Heng, Chang Baozhu, Chen Kun   

  1. Institute of Dermatology, Chinese Academy of Medical Sciences, Peking Union Medical College, Nanjing 210042
  • Received:1996-12-09 Revised:1997-01-30 Online:1997-06-15 Published:1997-06-15

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摘要： 为了明确CO2激光治疗尖锐湿疣过程中,烟尘中是否有HPV存在,采用PCR方法对尖锐湿疣患者治疗时烟尘标本和组织块标本进行HPV6和11型DNA检测。结果:21例组织块中,19例阳性;从距激光烧灼部位5cm(21例)和50cm(12例)处收集的烟尘标本中,无1例阳性。实验中未发现烟尘中及不同的吸附材料(无纺布、纱布和擦镜纸)存在对HPV检测有抑制作用的物质。本实验的结果提示:在用大功率CO2激光治疗疣时,其烟尘中无HPV,不会对周围人群造成危害。

关键词: 尖锐湿疣, 人类乳头瘤病毒, 二氧化碳激光, 烟尘

Abstract: In order to study whether there are human papillomaviruses (HPV) in the vapor during CO2 laser treatment of condyloma acuminatum, the vapor and skin lesions were detected for HPV DNA 6 and 11 by PCR. Result: 19 of 21 skin lesions were positive for HPV DNA. The vapor specimens collected 5 cm (21 samples) and 50 cm (12 samples) from the laser treated area were all negative. No inhibitory substances which influence the detection of HPV DNA were found in the vapor and vapor adsorbed materials. The results of this study suggest that no HPV DNA were found during treating genital warts by high power CO2 laser.

Key words: Condyloma acuminatum, Human papillomavirus, Carbon dioxide laser, Vapor