中华皮肤科杂志 ›› 1996, Vol. 29 ›› Issue (6): 408-411.

• 论著 • 上一篇    下一篇

面部皮炎的病因学研究

吴晓婕, 王侠生, 方丽华   

  1. 上海医科大学皮肤病研究所 200040
  • 收稿日期:1995-11-01 修回日期:1996-04-05 出版日期:1996-12-15 发布日期:1996-12-15
  • 基金资助:
    国家教委博士点课题基金

Studies on the Pathogenic Factors of Facial Dermatitis

Wu Xiaojie, Wang Xiasheng, Fang Lihua   

  1. Institute of Dermatology, Shanghai Medical University, Shanghai 200040
  • Received:1995-11-01 Revised:1996-04-05 Online:1996-12-15 Published:1996-12-15

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摘要： 为了对面部皮炎的病因进行研究,我们选择了81例临床上无明确致敏物接触史的面部皮炎患者,对他们进行致病因素的调查,其中包括45例季节性,36例非季节性患者,并选择了17例健康者作为正常对照,168例化妆品皮炎患者作为病例对照.本研究选用欧抗斑试、花粉挑刺、血清总IgE的测定、血清特异性IgE(螨)的测定和指血嗜酸粒细胞绝对计数等方法进行病因学的研究.研究结果显示,季节组和非季节组欧抗斑试的阳性率均明显高于健康组(P<0.05);面部皮炎患者对粉尘螨的阳性率明显高于健康组(P<0.05);季节组花粉挑刺阳性率明显高于非季节组和健康组(P<0.05),其中,春季发病者对春季花粉的阳性率明显高于对秋季花粉的阳性率(P<0.05),秋季发病者对秋季花粉的阳性率明显高于对春季花粉的阳性率(P<0.05).本研究的结果表明,花粉是季节性面部皮炎的重要致病因素,非季节性面部皮炎的发病可能对某些化学成份过敏有关.此外,粉尘螨也可能是面部皮炎的致病因素之一.关于面部皮炎的发病机理可能与IgE介导的皮肤变态反应有关.

关键词: 皮炎,面部, 花粉, 免疫球蛋白E类

Abstract: Eighty one cases of facial contact derm atitis with no clear history of contact with alergens,in cluding 45 seasonal and 36 nonseasonal cases were studied.17 healthy volunteers and 168 patients with cosmetic dermatit is were chosen as two control groups.The results were as folows:(1)The positive rates of European Standard Alergen Series Patch Test were much higher in seasonal and nonseasonal groups than in healthy group.(2)The positive rate to mite in facial derm atitis groups was much higher than that in healthy group.

Key words: rmatitis, facial, Polen, IgE