中华皮肤科杂志 ›› 1992, Vol. 25 ›› Issue (1): 29-31.

• 论著 • 上一篇    下一篇

恶性黑素瘤与色素痣显微分光光度计DNA定量研究

高天文, 刘荣卿, 叶庆佾, 唐书谦, 钟白玉   

  1. 第三军医大学第一附属医院皮肤科, 重庆 630038
  • 收稿日期:1990-10-22 修回日期:1991-03-19 出版日期:1992-02-15 发布日期:1992-02-15

DNA Analyals of Malignant Melanoma and Melanorytlc Nevi With Microepectro-pho-tometry

GAO Tian-Wen, LIU Rong-Qing   

  1. South-Westem Hospital, The Trhird Military Medical College, Chongqing, 630038
  • Received:1990-10-22 Revised:1991-03-19 Online:1992-02-15 Published:1992-02-15

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摘要： 应用显微分光光度计测定81例黑素细胞肿甜细胞核DNA含最及核面积.发现：普通后天天性痣、先天性小痣、先天性巨痣及恶性黑素瘤的DNA含最依次递增;各型色素痣之间、各型色素痣与各型恶性黑素瘤之间,DNA含量差异显著.结果提示:一直争论中的先天性小痣的生物学特性有别于后天性痣,显微分光光度计DNA定量对黑素细胞肿瘤的良恶性鉴别诊断有一定意义.

关键词: 黑素瘤, 脱氧核糖核酸, 肿瘤

Abstract: In the present stdy，the DNA contents werc quantitated on 81 cases of melanocytic tumors with microspectrophotometry.We found the following results: The DNA contents increased successively in common acquired nevi，congenital small nevi, congenital giant nevi, and malignant melanoma.

Key words: Melanoma, DNA, neoplasm