中华皮肤科杂志 ›› 1988, Vol. 21 ›› Issue (6): 355-357.

• 论著 • 上一篇    下一篇

少菌型麻风用利福平和氨苯砜短期治疗的初步疗效观察

李文忠1, 叶干运1, 陶明波2, 罗西谷2, 严良斌1, 陈祥生1, 朱学思2, 吕绍泉2, 贺挺书2, 邹玉生2, 王惠斌2, 季峰3   

  1. 1. 中国医学科学院皮肤病研究所;
    2. 扬州市皮肤病防治所暨协作医院;
    3. 江苏省东台县皮肤病防治所
  • 收稿日期:1987-11-20 修回日期:1988-02-22 出版日期:1989-02-15 发布日期:1989-02-15

Results of six-month treatment of paucibacillary leprosy patients with rifampicin and dapsone

LI Wen-Zhong1, YE Gan-Yun1   

  1. Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing
  • Received:1987-11-20 Revised:1988-02-22 Online:1989-02-15 Published:1989-02-15

摘要: 本文报告61例未治疗过的少菌型麻风用WHO推荐的少菌型麻风方案治疗半年的疗效观察并随访至2年.结果示治疗6个月时病情活动者为邪例(86.9%),不活动指数为0.13,疗后12个月时随访病情活动者21例(34.3%),不活动指数为0.66.有37例随访了两年,活动性病例为3例(8.1%),不活动指数为0.92.表明少菌型麻风用RFP和DDS治疗半年即停止所有扰麻风治疗看来是不适当的,建议在6个月后继续单用DDS治疗2年或直至病情不活动.

Abstract: The effects of six months of treatment with rifampicin (RFP) and dapsone (DDS) recommended by WHO in 61 untreated paucibacillary leprosy patients are reported through 2 years follow-up. At the end of six months of treatment, 53 cases (86.9%) remained active with an inactivity index of 0.13, and at the time of 12 months of follow-up, 21 cases (34.3%) were active,with an inactivity index of 0.66.