中华皮肤科杂志 ›› 1988, Vol. 21 ›› Issue (4): 200-202.

• 论著 • 上一篇    下一篇

皮肤淀粉样变皮疹的直接免疫荧光观察

是元甫, 章青, 刘季和, 孔庆英, 曾学思, 桑红桂, 李阿梅   

  1. 中国医学科学院皮肤病研究所
  • 收稿日期:1987-04-15 修回日期:1987-07-08 出版日期:1988-08-15 发布日期:1988-08-15

Observation on cutaneous amyloidosis lesions by direct immunofluorescence method

Shi Yuan-fu, Zhang Qing   

  1. Institute of Dermctology, Chinese Academy of Medical Sciences, Nanjing
  • Received:1987-04-15 Revised:1987-07-08 Online:1988-08-15 Published:1988-08-15

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摘要： 本文报告应用直接免疫荧光技术,观察21例皮肤淀粉样变的免疫病理特征.发现在邻近表皮的真皮,特别是乳头部位,有免疫球蛋白和补体的沉积,少数病例IgG或IgM沿着表皮、真皮之间或基底膜带部位沉积.并讨论了可能的病理诊断上的意义.

Abstract: In this paper immunopathologic characteristics of 21 cases of cutaneous amyloidosis were observed with direct immunofluorescence method. It was found that in some areas adjacent to the epidermis, especially in the papillary body, there were immunoglobulin and complement depositions, and in a few cases IgG or IgM were deposited along the dermal-epidermal junction, or basement membrane zone. The possible diagnostic significance of the pathology was discussed.