中华皮肤科杂志 ›› 1986, Vol. 19 ›› Issue (1): 7-9.

• 论著 • 上一篇    下一篇

系统性红斑狼疮136例诊断分析

徐世正, 周心房   

  1. 湖北医学院一附院
  • 收稿日期:1985-01-21 修回日期:1985-05-07 出版日期:1986-02-15 发布日期:1986-02-15

  • Received:1985-01-21 Revised:1985-05-07 Online:1986-02-15 Published:1986-02-15

摘要: 本文对136例系统性红斑狼疮的诊断分析表明:新发病例以15-25岁青年为主,女性发病为男性的14倍以上.用美国风湿病协会1982年修订的新标准诊断,敏感性为98.9%,比原标准提高11.95%,缩短确诊时间4个月以上(P<0.001).提高诊断敏感性和特异性的关键是抗核抗体和抗双链DNA杭体试验.

Abstract: The authors made a diagnostic analysis of 136 cases of systemic lupus erythematosus (SLE). The result showed that newly developed cases of SLE were mainly young females of 15-25 years of age.Pemales were over 14 times more than the males.The sensitivity of 1982 ARA revised criteria For the classification of SLE was 98.9 percent. It is 11.95 percent more sensitive than the 1971 ARA criteria. The duration for establishing the diagnosis shortened for more than 4 months (P<0.001). The key of raised sensitivity and specificity of the revised criteria is the inclusion of ANA and anti-dsDNA antibody tests.