中华皮肤科杂志 ›› 1984, Vol. 17 ›› Issue (2): 73-74.

• 论著 •    下一篇

草样肉芽肿浸润细胞免疫组织化学表现型的鉴定

顾绍裘, Wasserman. J., Biberfeld. P   

  • 出版日期:1984-06-15 发布日期:1984-06-15

In situ identification of immunohistochemical phenotype in the infiltrates of granuloma fungoides

Gu Shaoqui   

  • Online:1984-06-15 Published:1984-06-15

摘要: 应用各种针对T淋巴细胞、T淋巴细胞亚类、B淋巴细胞、单核细胞以及Ia抗原的单克隆及多克隆抗体,对2例覃样肉芽肿的特异性皮损内浸润细胞,用冰冻切片及间接免疫过氧化酶技术进行鉴定.结果为在浸润区内大部份细胞具有T辅助细胞的表面标志,并且Ia抗原阳性.

Abstract: Two patients, with mycosis fungoides have been reported. Frozen specific skin lesion sections were examined using indirect immuaoperoxidase tachnique with various monoclonal and polpclonal antibodies against T lymphocyte, T subsets, B lymphocyte, monocyte and Ia antigen. In the cases examined a predominance of cells with helper T cell markers and Ta positive was found. The discrepancy of some results were discussed.