中华皮肤科杂志 ›› 1982, Vol. 15 ›› Issue (3): 145-148.

• 论著 • 上一篇    下一篇

HLA和麻风相关的研究Ⅰ.中国汉族麻风病人HLA-A, B抗原的频率分布

徐可愚1, 马林1, 吴勤学1, 杨理合1, 叶干运1, 曹捐2, 王传基2   

  1. 1. 中国医学科学院皮肤病研究所麻风病研究宝;
    2. 江苏省溱湖医院
  • 出版日期:1982-09-15 发布日期:1982-09-15

HLA and leprosy： Ⅰ.Frequency incidence of HLA-A, B antigens among leprosy patients of Han Nationality

Xu Keyu1   

  • Online:1982-09-15 Published:1982-09-15

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摘要： 本文对109例江苏汉族麻风病人(L型61例,T型48例)进行了HLA-A,B分型,并分别与116名健康对照组相比较,观察到金部病人组和L型组中al,Aw30+w31抗原频率降低,B17抗原频率降珍极显著,校正后仍有显著性.T型组中Bw54 (w22)和Bw60(B40)抗原频率降低.但校正后无显著性.

Abstract: HLA-A,B typing was performed on 109 unrelated leprosy patients(L61 and T48)of Jiangsu Han nationality,with 116 healthy persons as control.Decreased frequency of HLA-al,Aw30+w31,B17 were found both ih all patients and in lepromatous groups,especially HLA-B17 showed statistical significance even after correction for the number of antigens tested:In tuberculoid leprosy decreased frequency of HLA-Bw54(w22),Bw60(B40) were observed..but showed no significance when corrected.