中华皮肤科杂志 ›› 1982, Vol. 15 ›› Issue (3): 149-152.

• 论著 • 上一篇    下一篇

70例瘤型麻风尸解外周神经千病变分析

刘子钧1, 丘钜世1, 何映芳2   

  1. 1. 中山医学倪病理教研室;
    2. 广州市皮肤病防治所
  • 出版日期:1982-09-15 发布日期:1982-09-15

Analysis of pathological changes of peripheral nerve trunks in 70 autopsies of lepromatous leprosy

Liu Zijun1   

  • Online:1982-09-15 Published:1982-09-15

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摘要： 检查70例瘤型麻风尸解外周神经千、共计807个组织块,发现各条神经病变的受累率是有差导的.病变受累最高的为尺神经(98.2%)、胖总神经(97.8%)及正中神经(90.2%).另外,检查了同时取材制片的双侧对应神经314对.发现单侧神经受累与双侧神经受累的比事约为1:5.因而认为瘤型麻风外周神经书病变不一定是对称.性弥漫性分布的.或者至少不是广泛性累及整条神经.从每条神经病变内细胞成份的差异来看,可分为进展期、消退期或静止期病变.在57例中外周神经干病变与皮肤病变对照的结果表明,皮肤麻风病变消退较外周神经者为快.

Abstract: Total number of 807 tissue blocks of various peripheral,nerve trunk's taken from 70 autopsied cases of lepromatous leprosy has been studied.It was found that the incidence rate of lesion in various nerve trunks was quite different,with the highest incideuce rate of lesion in ulnar nerve (98.2%),common fibular nerve (97.8%).and median nerve(90:2%).314 Pairs of bilateral tissue blocks taken from the same level of the same nerve have been examined,and the result showed that the ratio of unilateral nerve lesion to bilateral nerve lesion was generally 1:5.It means,that the lesions in nerve trunks of lepromatous leprosy were not generalized,symmetrically distributed,at least not diffusely affecting the entire length of the nerve.From the difference in cellular infiltrates of a given nerve,we can divide the lesions of nerve trunks into progressive stage,regressive stage,and quiescent stage.Correlating nerve trunk lesions to skin lesions in 57 cases studied,we found that the process of regression in skin lesion was faster than that in peripheral nerve trunk.