中华皮肤科杂志 ›› 2022, Vol. 55 ›› Issue (12): 1064-1067.doi: 10.35541/cjd.20220616

所属专题: 猴痘专题

• 猴痘病毒感染专栏·综述 • 上一篇    下一篇

【开放获取】猴痘病毒实验室检测技术的研究进展

徐文绮   周潜1    李岷2    陈祥生1    林彤2    尹跃平1   

  1. 1中国医学科学院、北京协和医学院皮肤病研究所参比实验室,南京  210042;2中国医学科学院、北京协和医学院皮肤病医院,南京  210042
  • 收稿日期:2022-09-02 修回日期:2022-09-30 发布日期:2022-12-05
  • 通讯作者: 尹跃平 E-mail:yinyp@ncstdlc.org

Laboratory testing techniques for monkeypox virus

Xu Wenqi1, Zhou Qian1, Li Min2, Chen Xiangsheng1, Lin Tong2, Yin Yueping1   

  1. 1Reference Laboratory of STD, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China; 2Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Received:2022-09-02 Revised:2022-09-30 Published:2022-12-05
  • Contact: Yin Yueping E-mail:yinyp@ncstdlc.org

摘要: 【摘要】 猴痘是一种由猴痘病毒感染所致的人兽共患病毒性疾病。2022年,猴痘首次在非洲以外地区广泛社区传播,成为国际关注的突发公共卫生事件。准确有效的检测方法对于猴痘病毒感染的诊断与筛查尤为重要。本文综述近年来猴痘病毒的实验室检测技术,比较镜检法、培养法、核酸检测法与免疫学方法的原理和检测性能。

关键词: 猴痘病毒, 猴痘, 核酸检测, 免疫学试验

Abstract: 【Abstract】 Monkeypox is a zoonotic viral disease caused by monkeypox virus infection. Monkeypox has become a public health emergency of international concern, since it first spread widely in many regions outside Africa in 2022. Accurate and effective detection methods are particularly important for the diagnosis and screening of monkeypox virus infection. This review summarizes laboratory testing techniques for monkeypox virus in recent years, and compares principles and detection performance of microscopy, culture, nucleic acid testing and immunological methods.

Key words: Monkeypox virus, Monkeypox, Nucleic acid test, Immunological tests