玫瑰痤疮的病理生理发病机制研究进展

doi:10.35541/cjd.20200178

中华皮肤科杂志 ›› 2022, Vol. 55 ›› Issue (5): 446-449.doi: 10.35541/cjd.20200178

玫瑰痤疮的病理生理发病机制研究进展

宋晓婷,刘擘,陈玉迪,赵作涛

北京大学第一医院皮肤性病科国家皮肤与免疫疾病临床医学研究中心北京市皮肤病分子诊断重点实验室，北京 100034

收稿日期:2020-02-26 修回日期:2020-07-30 发布日期:2022-04-29
通讯作者: 赵作涛 E-mail:zhaozuotaotao@163.com
基金资助:
国家自然科学基金中德合作项目（GZ901）

Pathophysiological pathogenesis of rosacea

Song Xiaoting, Liu Bo, Chen Yudi, Zhao Zuotao

Department of Dermatology and Venereology, Peking University First Hospital, National Clinical Research Center for Skin and Immune Diseases, Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing 100034, China

Received:2020-02-26 Revised:2020-07-30 Published:2022-04-29
Contact: Zhao Zuotao E-mail:zhaozuotaotao@163.com
Supported by:
Joint Sino-German Research Project of National Natural Science Foundation of China and DFG（GZ901）

摘要/Abstract

摘要： 【摘要】玫瑰痤疮发病机制尚未完全阐明，目前认为遗传因素、皮肤局部免疫失衡、神经免疫功能和神经血管环路紊乱、皮肤屏障功能异常、微生物菌群失调等均参与了玫瑰痤疮的发生发展。本文综述玫瑰痤疮的病理生理发病机制研究进展。

关键词: 红斑痤疮, 病理过程, 神经免疫调节, 局部免疫失衡, 神经免疫, 皮肤屏障功能

Abstract: 【Abstract】 The pathogenesis of rosacea has not been fully elucidated. It is currently believed that genetic factors, local skin immune imbalance, neuroimmune and neurovascular dysfunction, skin barrier function abnormalities, microbiota imbalance, etc., are all involved in the occurrence and development of rosacea. This review summarizes research progress in the pathophysiological pathogenesis of rosacea.

Key words: Rosacea, Pathologic processes, Neuroimmunomodulation, Local immunological imbalance, Neuroimmunity, Skin barrier function

宋晓婷刘擘陈玉迪赵作涛. 玫瑰痤疮的病理生理发病机制研究进展[J]. 中华皮肤科杂志, 2022,55(5):446-449. doi:10.35541/cjd.20200178

Song Xiaoting, Liu Bo, Chen Yudi, Zhao Zuotao. Pathophysiological pathogenesis of rosacea[J]. Chinese Journal of Dermatology, 2022, 55(5): 446-449.doi:10.35541/cjd.20200178

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玫瑰痤疮的病理生理发病机制研究进展

Pathophysiological pathogenesis of rosacea

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