Chinese Journal of Dermatology ›› 1993, Vol. 26 ›› Issue (6): 349-351.

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DNA Content and Silver Staining Nucieolar Organizer Region Protein in Cutaneous Malignant Melanoma

DING Zheng-Yun, LIN Yuan-Zhu, LIANG ZU-Qi   

  1. Department of Dermatology, The Fourth Hospital of Hebei Medical College, Shijiazhuang 050011
  • Received:1992-10-30 Revised:1993-02-25 Online:1993-12-15 Published:1993-12-15

Abstract: DNA content,cellular proliferative featares and silver staining nucleolar organizer rcgian(AgNORs) counts in 32 patients with eutaneous malignant melanoma(CMM),21 patients with nevus cell news(NN) and 3 normal controls were quantitatively studied by FCM and AgNORs technique and the correlation between them were examined.The results showed that all normal shin and NN were diploid of 29 CMM,4 were diploid,25 were aneuploid.S-phase fraction(SPE) and proliferative index(PI) were significantly higher in CMM than those in NN(P

Key words: DNA, Nucleolus organizer, region, Melanoma