Abstract: Objective To study the clinical features of follicular occlusion triad,and whether it is a hereditary disease.Methods Based on the clinical examination of a case who developed squamous cell carcinoma secondary to follicular occlusion triad,the pedigree of the patient was surveyed and analyzed.Results There were a total of thirteen patients in this pedigree,the age of onset was about 20 years old.The clinical features and laboratory examination of the proband was consistent with follicular occlusion triad.Conclusions Hereditary factor is important in the pathogenesis in follicular occlusion triad,and the disease maybe an autosomal dominant inherited disease.

Key words: Follicular occlusion triad, Carcinoma,squamous cell, Pedigree, Skin diseases,genetic