萱草花提取液及表皮生长因子对人真皮成纤维细胞增殖的作用

Abstract

Abstract: Human dermal fibroblasts from 5 normal adult donors were treated with EHCB, EGF, and EHCB combined with EGF for 7 days respectively.The fibroblast proliferation in each group was determined by counting the cell numbers.Our data indicate that EHCB inhibits the fibroblast proliferation(P<0.01), whereas EGF enhances the fibroblast proliferation (P<0.01).Interestingly, in the group of EHCB plus EGF,fibroblast proliferation was far more slow than that in EGF group.The article also discusses the possible pharmacological mechanism of EHCB and EGF on fibroblast proliferation.

Key words: Fibroblasts, Hemerocallis citrina barroni, Epidermal growth factor

HE Cheng-Xiong. Effects of Extract from Hemerocallis Citrina Barroni (EHCB) and Epidermal Growth Factor (EGF) on Human Dermal Fibroblast Proliferation[J].Chinese Journal of Dermatology, 1994, 27(4): 218-220,269.

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Effects of Extract from Hemerocallis Citrina Barroni (EHCB) and Epidermal Growth Factor (EGF) on Human Dermal Fibroblast Proliferation

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