Abstract: In order to study the cause why the patients with psoriasis are susceptible to complicate with cardiovascular diseases, we have determined the levels of serum apolipoprotein A-I, B-100, cholesterol and triglyceride in 30 cases of patients with psoriasis vulgaris by immunoquantitative, enzyme and triazole methods. The results showed that in comparison with the control group the levels of apolipoprotein A-I and triglyceride were normal, the levels of apolipoprotein B-100 and cholesterol increased (both P<0.05), and they were positively correlated (P<0.05), the ratio of apolipoprotein A-I over B-100 decreased(P<0.05), and was negatively correlated to cholesterol (P<0.05). The results of the study indicate that the increased level of apolipoprotein B-100 and the decreased ratio of apolipoprotein A-I over B-100 result in the increase of the level of serum cholesterol and the onset of the cardiovascular diseases.

Key words: Psoriasis, Apolipoproteins