Chinese Journal of Dermatology ›› 2011, Vol. 44 ›› Issue (5): 333-335.
• Original articles • Previous Articles Next Articles
2, 2
Received:
Revised:
Online:
Published:
Abstract:
Objective To make a nationwide external quality assessment for drug sensitivity testing of Neisseria gonorrhoeae, analyze the problems in and factors associated with the drug sensitivity testing, and to enhance the quality of drug sensitivity testing of N. gonorrhoeae at different monitoring sites. Methods Samples were uniformly delivered to monitoring sites by express mail service. Test results were analyzed in the National Center for STD Control, and the evaluation results were fed back to these monitoring sites. Results A total of 105 quality control samples were delivered from 2007 to 2009, with a response rate of 88.57% (93/105). Thirteen monitoring sites were enrolled in the external quality assessment, including 9 laboratories in 2007, 9 in 2008 and 13 in 2009. The total percentage amounted to 77.42% (24/31) for qualified laboratories during the 3 years, including 6 laboratories in 2007, 7 in 2008 and 11 in 2009. The coincidence rate increased for the detection of penicillinase-producing N. gonorrhoeae (PPNG), N. gonorrhoeae with chromosome-mediated ciprofloxacin resistance, and N. gonorrhoeae with chromosome-mediated spectinomycin resistance, and declined for the detection of N. gonorrhoeae with plasmid-mediated high level tetracycline-resistance (TRNG) and N. gonorrhoeae with chromosome-mediated ceftriaxone resistance. Conclusions The 3-year external quality assessment reveals an improvement in the overall quality of drug sensitivity testing of N. gonorrhoeae at national monitoring sites; the accuracy is improved markedly for the detection of PPNG, N. gonorrhoeae with resistance to spectinomycin and ciprofloxacin, but is needed to increase for the detection of ceftriaxone-resistant N. gonorrhoeae and TRNG.
Key words: external quality assessment
0 / / Recommend
Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks
URL: http://www.pifukezazhi.com/EN/
http://www.pifukezazhi.com/EN/Y2011/V44/I5/333
参考文献 1 叶顺章,苏晓红,王千秋,等.淋球菌耐药监测15年[J].中国性科学,2004,13(1):1-8. 2 王秀茹主编.预防医学微生物学及检验技术[M].北京:人民卫生出版社,2002:977-981. 3 刘锡光主编.现代诊断微生物学[M]. 北京:人民卫生出版社,2002 ,285-286. 4 周新,涂植光.临床生物化学和生物化学检验[M].北京:人民卫生出版社,2003,43-47.
Cited