Livin和Smac在尖锐湿疣组织中的表达

Abstract

Abstract:

Objective To explore the expressions of Livin and Smac in condyloma acuminatum （CA） tissue and their roles. Methods The expressions of Livin and Smac were analyzed by immunocytochemical staining with streptavidin-peroxidase （SP） in tissue specimens from the lesions of 58 patients with CA and foreskin of 20 normal human controls. Results The detection rates of Livin and Smac were 81.03%（47/58）and 77.59% （45/58） in CA lesions, respectively, compared to 25.00% （5/20） and 35.00% （7/20） in the controls, respectively. The expressions of Livin and Smac varied from positive （++） to strongly positive （+++） in CA lesions, and from negative （-） to positive （++） in the controls （both P < 0.05）. A positive correlation was found between the expression of Livin and Smac in CA lesions （r = 0.373, P < 0.01）. Conclusion There is an overexpression of Livin and Smac in CA tissue, which may be involved in the occurrence and development of CA.

Key words: Apoptosis

References

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Expressions of Livin and Smac in condyloma acuminatum tissue

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