Abstract:

We report here is about four cases with BCCs confirmed by histopatho- logy, whom have been treated by systemic acitretin and topical 0.1% retinoc acid cream. The four cases with BCCs showed good response to acitretin therapy. The patients were continued to be follows up every 4 weeks for clinical response and side effects occurred. The final follow-up for the 4 cases were 6 months to 4 years after the tumour was completely cleared. During treatment and follow-up, laboratory results remained within normal limits and examined by histopathology after the final follow up. These cases showed that the clinical signs and symptoms were completely cleared and no severe adverse effects were reported during the time on treatment and follow up, highlighting the therapeutic potential of oral acitretin in treatment of BCCs. The investigation was indicated that acitretin might be considered as a novel method of therapy for facial BCCs in aged person.