Abstract: 【Abstract】 Objective To analyze the willingness-to-pay （WTP） for the treatment of acute facial dermatitis with red and yellow light from light-emitting diodes （LEDs）, and to evaluate their cost-effectiveness. Methods A questionnaire survey was conducted on outpatients with or without acute facial dermatitis, which mainly manifested as erythema and swelling, in Department of Dermatology, Xiangya Hospital from August 2019 to June 2020. The WTP for the treatment of acute facial dermatitis of varying severity with red and yellow light from LEDs were investigated, clinical data on the prevalence of facial skin diseases, previous medical visits and quality of life were collected, and a benefit-cost analysis was conducted. Logistic regression analysis was conducted to investigate factors influencing the patients′ WTP for the LED treatment. Results The median WTP of the subjects were 200, 300 and 300 RMB yuan for the treatment of three cases of acute facial dermatitis of increasing severity assumed to require 1-, 3-, and 5-session LED treatments respectively, and the WTP for the treatment of case 2 and case 3 was higher than the cost of 1-session LED treatment （217 RMB yuan）. The subjects with high family incomes （≥ 100 000 RMB yuan/year） were significantly more willing to pay for the treatment than those with low family incomes （< 100 000 RMB yuan/year） （case 1: 40.46% vs. 27.50%, χ2 = 7.00, P = 0.008; case 2: 60.69% vs. 44.5%, χ2 = 9.75, P = 0.002; case 3: 51.20% vs. 48.8%, χ2 = 6.54, P = 0.011）, and the subjects who never suffered from facial dermatitis were significantly more willing to pay for the treatment than those who ever suffered （case 1: 35.49% vs. 28.82%, χ2 = 1.56, P = 0.212; case 2: 56.10% vs. 42.34%, χ2 = 5.92, P = 0.015; case 3: 68.32% vs. 56.75%, χ2 = 4.58, P = 0.032）. No significant difference in the WTP was observed among patients with different facial dermatoses, different degrees of impairment on quality of life, or different treatment experience（all P＞0.05）. Conclusion The cost of red and yellow light irradiation from LEDs for the treatment of acute facial dermatitis manifesting as erythema and swelling was highly acceptable in this population, and it is worthy of clinical promotion.

Key words: red and yellow LED, willingness to pay, facial dermatitis, cost-benefit analysis.