Chinese Journal of Dermatology ›› 2017, Vol. 50 ›› Issue (7): 478-481.

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Dermoscopic features of primary cutaneous amyloidosis

Yi-Xin LUO1,Cheng CHI2, 1, 1, 1,Jie Liu   

  • Received:2017-02-27 Revised:2017-04-06 Online:2017-07-15 Published:2017-07-03
  • Contact: Jie Liu E-mail:Liujie04672@pumch.cn
  • Supported by:
    The role and molecular mechanism of TOX in mycosis fungoides

Abstract: Luo Yixin, Liu Jie, Chi Cheng, Wang Shiqi, Qu Tao, Liu Yuehua, Jin Hongzhong Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China Corresponding author: Liu Jie, Email: Liujie04672@pumch.cn 【Abstract】 Objective To describe common dermoscopic features of primary cutaneous amyloidosis (PCA), and to explore the application value of dermoscopy in assisting the diagnosis of PCA. Methods Seventeen patients with PCA were collected from Department of Dermatology of Peking Union Medical College Hospital between April 2014 and December 2016. A total of 45 skin lesions were subjected to dermoscopy, and their dermoscopic features were analyzed. Results The common dermoscopic features of PCA included central hubs, which could be white, brown or scar?like areas, various pigment structures and shiny white streaks. Dermoscopy showed that central hubs could be observed in all the lesions (100%), while white center hubs alone were observed in 14 (31%) lichenoid lesions, both white center hubs and scar?like areas in 5 (11%) lichenoid lesions, brown center hubs alone in 8 (18%) macular lesions, both white and brown center hubs in 6 (13%) lichenoid lesions and 17 (38%) macular lesions. All the lesions showed various pigment structures. Shiny white streaks were observed in 4 (9%) lichenoid lesions. Conclusion Dermoscopy has good application value in assisting the diagnosis of PCA.

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