Chinese Journal of Dermatology ›› 2016, Vol. 49 ›› Issue (3): 219-222.

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Antihypertensive agent-induced drug eruptions: a literature review

SU HuiChun1,2, WHANG Baoxi4   

  • Received:2015-06-02 Revised:2015-07-10 Online:2016-03-15 Published:2017-03-20

Abstract: Su Huichun, Yao Xu, Wang Baoxi Department of Allergy and Rheumatology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China (the current affiliation of the third author was Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100144, China) Corresponding authors: Yao Xu, Email: dryao_xu@126.com; Wang Baoxi, Email: wangbx@ncstdlc.org 【Abstract】 There are various kinds of antihypertensive agents with complex chemical structures. Common antihypertensive agents are divided into 5 classes, including diuretics, calcium antagonists, angiotensin-converting enzyme inhibitors, angiotensin Ⅱ receptor blockers and β-blockers, and can cause various types of drug eruptions. This review summarizes clinical characteristics, possible pathogenesis, treatment and consequences of antihypertensive agent-induced drug eruptions, including angioedema, and lupus erythematosus-like, psoriasis-like, eczematoid, herpetiform or lichen planus-like drug eruptions, in hope to facilitate their early detection, diagnosis and treatment, and to provide information and ideas for clinical and basic researches into them.