Abstract:

Zhu Liping, Liu Haiyang, Pang Qin, He Li Kunming Medical University, Kunming 650032, China （Zhu LP）; Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650051, China （Liu HY）; Winona Medical Cosmetic Center, Kunming 650100, China （Pang Q）; Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Yunnan Institute of Dermatology and Venereology, Yunnan Engineering and Technology Research Center, Kunming 650032, China （He L） Corresponding author: He Li, Email: helikm2662@126.com 【Abstract】 Melasma is a common cutaneous disorder of pigment metabolism with complex etiology and pathogenesis. Combination therapy has been preferred by dermatologists for better therapeutic effects and less adverse reactions compared with monotherapy. At present, the treatment of melasma is diversiform, mainly including oral or topical drugs, lasers or photon therapy and combination therapy, etc. Individualized treatment is recommended based on etiology, clinical course and types of melasma, as well as previous treatment history. Combination therapy, sequential therapy or supplement therapy should be included in the treatment of melasma.