1999-2006年南京地区淋球菌对环丙沙星耐药现状的分析

Abstract

Abstract: Objective To study ciprofloxacin resistance in Neisseria gonorrhoeae isolates in Nanjing City from 1999 to 2006.Methods Minimum inhibitory concentration(MIC)of ciprofloxacin was determined by agar dilution method in 1208 strains of N.gonorrhoeae isolated from outpatients in a STD clinic in Nanjing City.Results The prevalence of ciprofloxacin resistance increased from 83.93% in 1999 to 98.99% in 2006.Among these strains,71.61%(865/1208)were highly resistant(MIC≥4 mg/L)to ciprofloxacin.Conclusion In Nanjing City,ciprofloxacin resistance of N.gonorrhoeae is a significant public health issue.

Key words: Neisseria gonorrhoeae, Ciprofloxacin, Drug resistance,bacterial

QI Mu-ge, JIANG Fa-xing, DAI Xiu-qin, SUN Hou-hua, YE Shun-zhang, WANG Qian-qiu, SU Xiao-hong. Ciprofloxacin resistance in Neisseria gonorrhoeae in Nanjing City,1999-2006[J].Chinese Journal of Dermatology, 2007, 40(12): 720-721.

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Ciprofloxacin resistance in Neisseria gonorrhoeae in Nanjing City,1999-2006

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