Chinese Journal of Dermatology ›› 2014, Vol. 47 ›› Issue (11): 806-808.
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Abstract: Wu Chao*, Lu Changqing, Kang Dinghua, Sun Jun. *Department of Pathology, First People′s Hospital of Changzhou, Third Affiliated Hospital of Suzhou University, Changzhou 213003, China 【Abstract】 A 52-year-old female presented with unexplained thrombocytopenia for 29 years and a prunosus plaque on the right cheek for 9 years. She had ever been treated with glucocorticoids, which resulted in a slight improvement of the condition, but the platelet count remained below the normal range. During glucocorticoid tapering, she had administrated traditional Chinese medicines for a long peroid. Recently, the plaque on the cheek became swollen and painful with a progressive decrease in platelet count. Routine blood test showed that the count of white blood cells and platelets was 3.0 × 109/L and 2 × 109/L respectively, and the concentration of hemoglobin was 85 g/L. Computed tomography (CT) scan revealed multiple liver hemangiomas, one of which in the left liver lobe measured 14 cm × 5.7 cm in size. After medical treatment, the giant hemangioma in the left lobe was resected. Thereafter, the platelet count increased to 120 × 109/L with the subsidence of swelling of the right cheek. Postoperative pathological examination confirmed a diagnosis of giant cavernous hemangioma of the liver with extensive intravascular thrombosis and thrombus organization. Based on these findings, the case was diagnosed as adult Kasabach-Merritt syndrome.
Key words: Kasabach-Merritt syndrome, Case reports [Publication type]
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