Chinese Journal of Dermatology ›› 1989, Vol. 22 ›› Issue (3): 172-173.

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STUDY ON ENZYME-HISTOCHEMICAL AND ULTRASTRUCTURAL CHANGES IN PSORIATIC LESIONS

LI Jun1, Long Yan-Ling1   

  1. West China Medical Urarxrsity, Chengdu
  • Received:1987-12-28 Revised:1988-05-09 Online:1989-06-15 Published:1989-06-15

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Abstract: The skin lesions of 19 patients with psoriasis vulgaris were studied using enzyme-histochemical method and TEM. The result showcd that the activities of SDH, ICDH, MDH, CCO, NADHD and β-OH-BD in mitochondria decreased. This indicated that there were decreased oxidation function of energy supply of mitochondria in the epidermal cells of psoriatic lesion. The increase of numbcr and size of mitochondria observed under TEM might be a structural compensation for energy supply.