Chinese Journal of Dermatology ›› 1992, Vol. 25 ›› Issue (1): 25-28.

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Activity of Home-made Pefioxacin M.Leprae In Mice and Its Preliminary Effecto in the Treatment of Multibaciilary Leprosy

SHEN Jian-Ping1, LI Wen-Zhong1   

  1. Institute of Dermatology Chinese Academy of Medical Sciences, Nanjing, 210042
  • Received:1990-07-12 Revised:1990-12-27 Online:1992-02-15 Published:1992-02-15

Abstract: This paper report, the effects of home-made pefloxacin (PFLO) in the treatment of leprosy. The result showed that the growth delay of M.leprae in foot pads of infected mice after treatment with PFLO 150mg /kg daily for 80 days was 138 days with the bactericidal rate of 97.08%, Twelve previously untreWed multibacillary patients received orally PFLO 800mg/day for 6months.

Key words: Pefloxacin, Leprosy