Abstract: Two hundred and fifty cases of DLE are described including 80 males and 170 females. All cases have multiform skin lesions besides the discoid erythematons macules. Although some cases have systemic lesions, immunologic and hematologic abnormalities, the incidence of them is lower and the extent miler. The effective rate of Chinese herb Trigterygium hypoglaucum was 83 per cent in our patients. The relationship between DLE and SLE were discussed.