Abstract: Objective To investigate the clinical features of patients with Behcet's syndrome in Liaoning province.Methods The clinical data of 64 patients with Behcet's syndrome seen in Liaoning province between 2002 and 2005 were retrospectively analyzed and compared with those seen in other countries and other areas in China.Results The male-to-female ratio in the patients was 1:1.2,the age of onset of most patients was found to be between 20-39 years.Of the patients,100% had oral ulcers,70.3% had genital ulcers,46.9% had ocular lesions,81.3% had skin lesions,70.3% had positive pathergy reaction,and 12.5% had family histories.The frequency of joint involvement was 43.8%,renal involvement 35.9%,neurologic involvement 25.0%,gastrointestinal involvement 18.8%,vascular involvement 4.7%,cardiac involvement 1.6%,and epididymitis 1.6%.Erythema nodosum and joint involvement were more frequent in the females than in the males (both P<0.05),while gastrointestinal involvement was more frequent in the males than in the females (P<0.05).Laboratory findings showed that the frequency of increased peripheral blood ieukocytes was 21.9%,proteinuria 15.6%,hematuria 21.9%,elevated erythroeyte sedimentation rate 44%,elevated serum IgG,21.9%,elevated serum IgA 19.2%,and elevated serum IgM 10.6%.The frequencies of decreas e of serum C3 and C4 levels were 10.6% and 8.5%,respectively.Also,7.1% of the patients were positive for ANA,14.3% for ds-DNA antibody,9.5% for ENA antibody,and 30.0% for HLA-B*51 alleles.Conclusion The incidences of some clinical manifestations of Behcet's syndrome might be different in different geographical areas.

Key words: Behcet syndrome, Clinical analysis