Chinese Journal of Dermatology

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A survey of clinical manifestations and etiology in 380 patients with genital ulcer diseases

YE Shun-zhang, HAN Guo-zhu, LAI Wei-hong, SU Xiao-hong, YIN Yue-ping, WANG Qian-qiu, ZHONG Ming-ying   

  1. Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Received:2005-03-10 Online:2006-04-15 Published:2006-04-15

Abstract: Objective To understand the clinical manifestations and etiology in patients with sexually transmitted infections characteristic of genital ulcers.Methods Consecutive patients with genital ulcer diseases were recruited to collect clinical and epidemiological data,and underwent clinical and laboratory investigations,according to united criteria,in STD clinics in Nanjing,Dalian,and Shenzhen.The proportions of different etiologies and clinical manifestations were determined in genital ulcer diseases.Results In 380 patients with genital ulcer diseases,syphilis accounted for 40.26% (153),and genital herpes 43.95% (167).No case of chancroid or lymphogranuloma venereum was found.Most of the lesions were situated in coronary sulcus (46.67%) in men and on labium majus pudendi (50.70%) in women.Conelusion It is indicated that syphilis and genital herpes predominate in patients with genital ulcer diseases in our country at present,and that there is no laboratory-confirmed case of chancroid and lymphogranuloma venereum.

Key words: Ulcer, Sexually transmitted diseases