中华皮肤科杂志 ›› 1993, Vol. 26 ›› Issue (5): 279-281.

• 论著 • 上一篇    下一篇

新生儿红斑狼疮六例

冯树芳1, 郑昌竹2, 李雪瑞3, 李敬1, 谢长葵1   

  1. 1. 上海医科大学华山医院皮肤病教研组, 200040;
    2. 进修医师;
    3. 上海市儿童医晚
  • 收稿日期:1992-08-18 修回日期:1992-12-11 出版日期:1993-10-15 发布日期:1993-10-15

Neonatal Lupus Erythematosus： 6 Cases Reports

FENG Shu-Fang1, ZHENG Chang-Zhu2   

  1. Shanghai Huashan Hospital, Shanghai 200040
  • Received:1992-08-18 Revised:1992-12-11 Online:1993-10-15 Published:1993-10-15

PDF (PC)

363

赞

摘要： 随访红斑狼疮孕妇所生育的21个婴儿.发现新生儿红斑狼疮(NLE)5例.另1例见于同期普通门诊.观察结果显示皮损以暴光处之环形红斑为主.血清内均有抗Ro抗体.未见心脏损害.有NLE的患病母亲组.其抗Ro抗体的阳性率.显著高于无NLE的患病母亲组.故本病的发病与Ro抗体有一定关系.

关键词: 红斑狼疮, 新生儿

Abstract: We followed up 21 infants born to women with LE.Five infants had definite neonatal lupus crythematosus (NIE).During the same period,1 additional infant with NLE was found in our general clinic.There was annular erythema on the sun-eaposed in our patients.No cardic lesions in all infants were observed.The anti-Ro antibody was positive in all infants with NLE.The positive rate of anti-Ro antibody in LE mothers with NLE infants was higher than that in LE mothers with healthy infants.It is suggested that the pathogenesis of NLE be associated with anti-Ro antibody.

Key words: Lupus erythematosus, neonatal