进行性系统性硬化症伴发多发性肌炎

中华皮肤科杂志 ›› 1993, Vol. 26 ›› Issue (5): 276-278.

进行性系统性硬化症伴发多发性肌炎

赵晓丽¹, 汤晓芙², 苑超², 李本红³, 杜华³

1. 进修医师, 南京脑科医院, 210029;
2, 指导老师, 北京协和医院;
3. 北京协和医院肌电图室

收稿日期:1992-07-03 修回日期:1992-11-28 出版日期:1993-10-15 发布日期:1993-10-15

Progressive Systemic Sclerosis Associated with PolyEnyositis

ZHAO Xiao-Li¹, TANG Xiao-Fu²

Peking Union Medical College Hospital, Beijing 100730

Received:1992-07-03 Revised:1992-11-28 Online:1993-10-15 Published:1993-10-15

摘要/Abstract

摘要： 对81例确诊进行性系统性硬化症(PSS).又疑伴发多发性肌炎(PM)的患者进行肌电图(EMG)研究.发现(EMG)异常者55例(68%).血清肌酶升高68例(78%).EMG异常与临床肌肉症状、血清肌酶相关比较有统计学意义(P<0.05,P<0.01).认为48/81例(59%)患者符合PSSPMOS诊断标准.31例患者经临床和EMG动态随诊64次.复查血清肌酶59次.见两者恢复不同步.EMG上插入电位延长、运动单位电位平均时限及波幅等项恢复显著(P<0.01,P<0,05).讨论了PSS伴发PM的诊断.EMG诊断价值及PM的转归等.

关键词: 硬皮病, 全身性多发性肌炎

Abstract: EMG studies were made on 81 patients who had been diagnosed as progressive systemic Sclerosis (PSS) and considered to he associated with polymyositis (PM).We found 55 cases having abnormal EMG and 63 cages with elevation of muacie enzyme.EMG had positive correlation with clinical features and muscle enzymes (P<0.05,P<1.01),48/81 cases were considered suffering from a disease of progressiVe systemic sclerosis-polymyositis overlap syndrome.Diagnosis was based on the American Rheumatism Association (ARA) preliminary criteria for scleroderma and the criteria for PM/DM of Bohan and Peter.31 case were found to 6e increasingly improved,however not concurrently between EMG and CPK findings on follow up.There were dramatic decreasing of increased insertion irritability and polyphasic motor unit pottntials of short duration and small amplitude on EMG(P<0.01,P<0.05)

Key words: Scleroderma, systemic Polymyositis

赵晓丽, 汤晓芙, 苑超, 李本红, 杜华. 进行性系统性硬化症伴发多发性肌炎[J]. 中华皮肤科杂志, 1993, 26(5): 276-278.

ZHAO Xiao-Li, TANG Xiao-Fu. Progressive Systemic Sclerosis Associated with PolyEnyositis[J]. Chinese Journal of Dermatology, 1993, 26(5): 276-278.

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