中华皮肤科杂志 ›› 2013, Vol. 46 ›› Issue (2): 128-129.

• 研究报道 • 上一篇    下一篇

外阴阴道念珠菌病的致病菌群分析

徐海萍1,王桂芝2,王君2,臧运书2,葛红芬2,王莹莹3   

  1. 1. 青岛市第三人民医院
    2. 青岛大学医学院附属医院皮肤科
    3. 青岛大学医学院附属医院
  • 收稿日期:2012-05-11 修回日期:2012-05-20 出版日期:2013-02-15 发布日期:2013-02-01
  • 通讯作者: 王桂芝 E-mail:wangguizhi1956@163.com
  • 基金资助:
    青岛市应用基础科技计划项目

Analysis of Candida species causing vulvovaginal candidiasis

  • Received:2012-05-11 Revised:2012-05-20 Online:2013-02-15 Published:2013-02-01

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摘要： 目的 探讨青岛及周边地区外阴阴道念珠菌病致病菌的菌种特征。 方法 采用常规念珠菌培养方法鉴定菌种，包括沙氏培养基，血清芽管实验，CHROMagar念珠菌显色培养基及API 20C AUX酵母菌鉴定系统。结果 2011年5 ~ 11月共收集362例妇科门诊患者的阴道分泌物，病原学分析显示，念珠菌阳性例数为313例，总感染率为86.46%，菌种构成分布为白念珠菌275株，光滑念珠菌13株，近平滑念珠菌8株，热带念珠菌7株，克柔念珠菌5株，葡萄牙念珠菌1株，都柏林念珠菌1株，粘质红酵母菌1株，奥默毕赤酵母菌1株，粘性丝孢酵母菌1株。结论 白念珠菌仍是外阴阴道念珠菌病的常见致病菌，非白念以光滑念珠菌为主。

关键词: 念珠菌病，外阴阴道, 研究

Abstract: XU Hai-ping, WANG Gui-zhi, WANG Jun,ZANG Yun-shu, GE Hong-fen, WANG Ying-ying. Department of Dermatology, Affiliated Hospital of Medical College Qingdao University, Qingdao 266000, China Corresponding author: WANG Gui-zhi, Email: wangguizhi1956@163.com 【Abstract】 Objective To analyze Candida species causing vulvovaginal candidiasis in Qingdao and surrounding areas. Methods Vaginal discharge specimens were collected from 362 patients with suspected vulvovaginal candidiasis in the Affiliated Hospital of Qingdao University Medical College from May 2011 to November 2011, and subjected to routine fungal culture. The Candida isolates were identified by using Sabouraud dextrose agar, CHROMagar medium, germ tube test with serum, and API 20C AUX Clinical Yeast System. Results Totally, 313 （86.46%） Candida strains were isolated from the specimens of 362 patients. Of these Candida strains, 275 were identified as Candida albicans, 38 as non-albicans Candida species, including 13 Candida glabrata strains, 8 Candida parapsilosis strains, 7 Candida tropicalis strains, 5 Candida krusei strains, 1 Candida lusitaniae strain, 1 Candida dubliniensis strain, 1 Rhodotorula mucilaginosa strain, 1 Pichia ohmeri strain and 1 Trichosporon mucoides strain. Conclusions As far as vulvovaginal candidiasis is concerned, Candida albicans is still the most prevalent pathogen, and Candida glabrata appears to be the predominant species in pathogenic non-albicans Candida species.

中图分类号: 

  • R711.73