中华皮肤科杂志 ›› 1996, Vol. 29 ›› Issue (4): 226-228.

• 论著 • 上一篇    下一篇

78例可疑疱疹样皮炎病例分析

翁孟武, 苏伟, 徐明, 侯爱琴   

  1. 上海医科大学华山医院皮肤科 200040
  • 收稿日期:1995-07-09 修回日期:1995-10-10 发布日期:1996-08-15
  • 基金资助:
    博士点基金

Diagnosis of Dermatitis Herpetiformis——An Analysis of 78 Clinicaly Suspected Cases

Weng Mengwu, Su Wei, Xu Ming   

  1. Department of Dermatology, Hua Shan Hospital, Shanghai Medi-cal University, Shanghai 200040
  • Received:1995-07-09 Revised:1995-10-10 Published:1996-08-15

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摘要： 将10年来我院临床初诊疑诊为疱疹样皮炎的78例患者进一步作病理、免疫病理或免疫印迹检查发现,最后确诊疱疹样皮炎2例(占2.6%)、疱疹样天疱疮32例(41.0%)、线形IgA大疱病14例(18.0%)、类天疱疮12例(15.4%)、获得性大疱表皮松解症1例(1.3%),有17例(21.8%)尚未确诊.2例疱疹样皮炎均为男性,分别为27、29岁,无明显谷胶过敏性肠病史,对氨苯砜治疗有效.上述结果提示疱疹样皮炎在我国发病率很低,临床初诊疱疹样皮炎病例中,绝大部分为疱疹样天疱疮、线形IgA大疱病和类天疱疮,这对临床具有重要的指导意义.

Abstract: The diagnosis of 78 cases of clinically suspected dermatitis herpetiformis(DH) in last 10 years were studied by using histological,immunopathologic examination and immunobloting test.Re-sults: The definite diagnoses of these 78 cases were DH2 cases (2.6%),pemphigus herpetiformis (PH) 32 cases (41.0%),linear IgA disease (LAD) 14 cases (18.0%), bulous pemphigoid (BP) 12 cases (15.4%),and epidermolysis bulousa acquisita (EBA) 1 case (1.3%),another 17 cases (21.8%) could not be confirmed by DIF,salt-split skin DIF,ⅡF and immunobloting test.2 cases of DH was bothmale,27 and 29 years old respectively,no history of gluten-sensitive enteropathy and responded to therapy with dapsone.Conclusion:This study demonstrates that the incidence of DH in Chinaislower than that in Western countries.The majority of clinicaly suspected cases of DH in our clinic are patients with PH,LAD and BP,and only two cases are classic DH.

Key words: Dermatitis, herpetiformis