中华皮肤科杂志 ›› 2000, Vol. 33 ›› Issue (3): 165-166.

• 论著 • 上一篇    下一篇

性病门诊以生殖器溃疡为主要表现的疾病病因初探

王千秋, 钟铭英, 张津萍, 杨凭, 王广聚   

  1. 中国医学科学院、中国协和医科大学皮肤病研究所 南京 210042
  • 收稿日期:1999-12-07 出版日期:2000-06-15 发布日期:2000-06-15

The Etiology of Genital Ulcer Diseases in Sexually Transmitted Disease Clinics

WANG Qianqiu, ZHONG Mingying, ZHANG Jinping   

  1. Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042
  • Received:1999-12-07 Online:2000-06-15 Published:2000-06-15

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摘要： 目的 了解在性病门诊中,以生殖器溃疡为主要表现的疾病的病因.方法 在实验室建立了同时检测梅毒、生殖器疱疹和软下疳的复合PCR方法.同时进行暗视野显微镜检查和梅毒血清学检查.结果 复合PCR检测梅毒与暗视野显微镜检查和梅毒血清学检查有较好的一致性.在总计165例患者中,梅毒51例,生殖器疱疹52例,分别占30.9%和31.5%,未发现软下疳病例.62例(37.6%)未检出病原体.结论 在性病门诊中,生殖器溃疡性疾病以梅毒及生殖器疱疹占优势,而软下疳尚未发现.

关键词: 生殖器, 溃疡, 梅毒, 生殖器疱疹, 聚合酶链反应

Abstract: Objectives To investigate the etiology of genital ulcer diseases in sexually transmitted disease clinics.Methods The specimens from genital ulcers of 165 patients attending sexually transmitted disease clinics were detected for Haemophilus ducreyi,Treponema pallidum,and herpes simplex virus by a multiplex PCR,dark field microscopy and syphilitic serology.Results There were 51 (30.9%) cases of syphilis and 52 (31.5%) cases of genital herpes among 165 patients,respectively.No chancroid case was found.No pathogen was detected in remaining 62 (37.6%) patients.Conclusion Syphilis and genital herpes predominate in genital ulcer diseases in our sexually transmitted disease clinic patients.

Key words: Genitalia, Ulcer, Syphilis, Genital herpes, Polymerase chain reaction