反射式共聚焦显微镜辅助手术治疗外阴乳房外Paget病二例

doi:10.35541/cjd.20180711

中华皮肤科杂志 ›› 2021, Vol. 54 ›› Issue (8): 723-725.doi: 10.35541/cjd.20180711

反射式共聚焦显微镜辅助手术治疗外阴乳房外Paget病二例

孔令卓¹ 张韡² 单士军³ 吴信峰¹

¹中国医学科学院、北京协和医学院皮肤病医院整形美容科，南京 210042；²中国医学科学院、北京协和医学院皮肤病医院病理科，南京 210042；³厦门大学附属翔安医院皮肤科 361000

收稿日期:2018-08-22 修回日期:2020-04-11 发布日期:2021-08-02
通讯作者: 吴信峰 E-mail:wuxinfengdr@163.com

Reflectance confocal microscopy-assisted surgical treatment for two cases of extramammary Paget′s disease of the vulva

Kong Lingzhuo¹, Zhang Wei², Shan Shijun³, Wu Xinfeng¹

¹Department of Plastic Surgery, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China; ²Department of Pathology, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China; ³Department of Dermatology, Xiang′an Hospital of Xiamen University, Xiamen 361000, Fujian, China

Received:2018-08-22 Revised:2020-04-11 Published:2021-08-02
Contact: Wu Xinfeng E-mail:wuxinfengdr@163.com

摘要/Abstract

摘要： 【摘要】为了探索准确判断乳房外Paget病手术边界的方法，对2例经病理确诊为外阴原位乳房外Paget病的病例，术前使用反射式共聚焦显微镜确定肿瘤边界，以此为基础进行改良的扩大切除术。术后切缘行4点病理监测未见肿瘤残留，1年后随访未见复发。

关键词: 佩吉特病, 乳腺外, 显微镜检查, 共焦, 外科手术

Abstract: 【Abstract】 In order to develop a method to more accurately determine the surgical boundary of extramammary Paget′s disease, reflectance confocal microscopy was used to determine the tumor boundary followed by modified extended excision in 2 cases of pathologically diagnosed extramammary Paget′s disease of the vulva. No residual tumor was observed in the resection margins by postoperative pathological examination at 4 positions （12, 3, 6 and 9 o′clock）, and follow-up showed no recurrence 1 year later.

Key words: Paget disease, extramammary, Microscopy, confocal, Surgical procedures, operative

孔令卓张韡单士军吴信峰. 反射式共聚焦显微镜辅助手术治疗外阴乳房外Paget病二例[J]. 中华皮肤科杂志, 2021,54(8):723-725. doi:10.35541/cjd.20180711

Ling-Zhuo Kong ZHANG Wei Shi-Jun SHAN. Reflectance confocal microscopy-assisted surgical treatment for two cases of extramammary Paget′s disease of the vulva[J]. Chinese Journal of Dermatology, 2021, 54(8): 723-725.doi:10.35541/cjd.20180711

参考文献 9

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反射式共聚焦显微镜辅助手术治疗外阴乳房外Paget病二例

Reflectance confocal microscopy-assisted surgical treatment for two cases of extramammary Paget′s disease of the vulva

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