中华皮肤科杂志 ›› 2020, Vol. 53 ›› Issue (8): 668-672.doi: 10.35541/cjd.20180845
• 综述 • 上一篇
付玉娟 周炯 郑敏
收稿日期:
2018-10-29
修回日期:
2019-05-25
发布日期:
2020-07-31
通讯作者:
郑敏
E-mail:minz@zju.edu.cn
Fu Yujuan, Zhou Jiong, Zheng Min#br#
Received:
2018-10-29
Revised:
2019-05-25
Published:
2020-07-31
Contact:
Zheng Min
E-mail:minz@zju.edu.cn
摘要: 【摘要】 系统性免疫球蛋白轻链型淀粉样变性是因淀粉样蛋白原纤维聚集沉积引起的蛋白质错误折叠疾病,可导致器官不可逆性功能障碍。本文根据疾病危险分层详述本病的系统性治疗方法,低危系统性免疫球蛋白轻链型淀粉样变性患者适用化疗结合自体造血干细胞移植,中高危患者可用蛋白酶抑制剂如硼替佐米、卡非佐米及依沙唑米和免疫调节药物如来那度胺、泊马度胺及新型免疫制剂如达拉图马布、NEOD001等治疗。
付玉娟 周炯 郑敏. 系统性免疫球蛋白轻链型淀粉样变性的治疗进展[J]. 中华皮肤科杂志, 2020,53(8):668-672. doi:10.35541/cjd.20180845
Fu Yujuan, Zhou Jiong, Zheng Min. Treatment of systemic immunoglobulin light chain amyloidosis[J]. Chinese Journal of Dermatology, 2020, 53(8): 668-672.doi:10.35541/cjd.20180845
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