| ［1］ |
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL⁃beta［J］. Mol Cell, 2002,10（2）:417⁃426. doi: 10.1016/s1097⁃2765（02）00599⁃3.
|
| ［2］ |
Tartey S, Kanneganti TD. Differential role of the NLRP3 inflammasome in infection and tumorigenesis［J］. Immunology, 2019,156（4）:329⁃338. doi: 10.1111/imm.13046.
|
| ［3］ |
Gasparoto TH, de Oliveira CE, de Freitas LT, et al. Inflammasome activation is critical to the protective immune response during chemically induced squamous cell carcinoma［J］. PLoS One, 2014,9（9）:e107170. doi: 10.1371/journal.pone.0107170.
|
| ［4］ |
Neagu M, Constantin C, Caruntu C, et al. Inflammation: a key process in skin tumorigenesis［J］. Oncol Lett, 2019,17（5）:4068⁃4084. doi: 10.3892/ol.2018.9735.
|
| ［5］ |
Kolb R, Liu GH, Janowski AM, et al. Inflammasomes in cancer: a double⁃edged sword［J］. Protein Cell, 2014,5（1）:12⁃20. doi: 10.1007/s13238⁃013⁃0001⁃4.
|
| ［6］ |
Allen IC, TeKippe EM, Woodford RM, et al. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis⁃associated cancer［J］. J Exp Med, 2010,207（5）:1045⁃1056. doi: 10.1084/jem.20100050.
|
| ［7］ |
Zhang M, Jin C, Yang Y, et al. AIM2 promotes non⁃small⁃cell lung cancer cell growth through inflammasome⁃dependent pathway［J］. J Cell Physiol, 2019,234（11）:20161⁃20173. doi: 10. 1002/jcp.28617.
|
| ［8］ |
Broz P, Dixit VM. Inflammasomes: mechanism of assembly, regulation and signalling［J］. Nat Rev Immunol, 2016,16（7）:407⁃420. doi: 10.1038/nri.2016.58.
|
| ［9］ |
Sollberger G, Strittmatter GE, Grossi S, et al. Caspase⁃1 activity is required for UVB⁃induced apoptosis of human keratinocytes［J］. J Invest Dermatol, 2015,135（5）:1395⁃1404. doi: 10.1038/jid.2014.551.
|
| ［10］ |
Awad F, Assrawi E, Louvrier C, et al. Photoaging and skin cancer: is the inflammasome the missing link?［J］. Mech Ageing Dev, 2018,172:131⁃137. doi: 10.1016/j.mad.2018.03.003.
|
| ［11］ |
Kim KE, Cho D, Park HJ. Air pollution and skin diseases: adverse effects of airborne particulate matter on various skin diseases［J］. Life Sci, 2016,152:126⁃134. doi: 10.1016/j.lfs.2016. 03.039.
|
| ［12］ |
Ahmad I, Muneer KM, Chang ME, et al. Ultraviolet radiation⁃induced downregulation of SERCA2 mediates activation of NLRP3 inflammasome in basal cell carcinoma［J］. Photochem Photobiol, 2017,93（4）:1025⁃1033. doi: 10.1111/php.12725.
|
| ［13］ |
Drexler SK, Bonsignore L, Masin M, et al. Tissue⁃specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis［J］. Proc Natl Acad Sci U S A, 2012,109（45）:18384⁃18389. doi: 10.1073/pnas.1209 171109.
|
| ［14］ |
Sand J, Fenini G, Grossi S, et al. The NLRP1 inflammasome pathway is silenced in cutaneous squamous cell carcinoma［J］. J Invest Dermatol, 2019,139（8）:1788⁃1797.e6. doi: 10.1016/j.jid. 2019.01.025.
|
| ［15］ |
Farshchian M, Nissinen L, Siljamäki E, et al. Tumor cell⁃specific AIM2 regulates growth and invasion of cutaneous squamous cell carcinoma［J］. Oncotarget, 2017,8（28）:45825⁃45836. doi: 10. 18632/oncotarget.17573.
|
| ［16］ |
Verma D, Bivik C, Farahani E, et al. Inflammasome polymorphisms confer susceptibility to sporadic malignant melanoma［J］. Pigment Cell Melanoma Res, 2012,25（4）:506⁃513. doi: 10.1111/j.1755⁃148X.2012.01008.x.
|
| ［17］ |
da Silva WC, Oshiro TM, de Sá DC, et al. Genotyping and differential expression analysis of inflammasome genes in sporadic malignant melanoma reveal novel contribution of CARD8, IL1B and IL18 in melanoma susceptibility and progression［J］. Cancer Genet, 2016,209（10）:474⁃480. doi: 10. 1016/j.cancergen.2016.09.004.
|
| ［18］ |
Liu W, Luo Y, Dunn JH, et al. Dual role of apoptosis⁃associated speck⁃like protein containing a CARD （ASC） in tumorigenesis of human melanoma［J］. J Invest Dermatol, 2013,133（2）:518⁃527. doi: 10.1038/jid.2012.317.
|
| ［19］ |
Penuela S, Gyenis L, Ablack A, et al. Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype［J］. J Biol Chem, 2012,287（34）:29184⁃29193. doi: 10.1074/jbc.M112.377176.
|
| ［20］ |
Kerur N, Veettil MV, Sharma⁃Walia N, et al. IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma⁃associated herpesvirus infection［J］. Cell Host Microbe, 2011,9（5）:363⁃375. doi: 10.1016/j.chom.2011.04. 008.
|
| ［21］ |
Singh VV, Kerur N, Bottero V, et al. Kaposi′s sarcoma⁃associated herpesvirus latency in endothelial and B cells activates gamma interferon⁃inducible protein 16⁃mediated inflammasomes［J］. J Virol, 2013,87（8）:4417⁃4431. doi: 10.1128/JVI.03282⁃12.
|
| ［22］ |
Zhong FL, Mamaï O, Sborgi L, et al. Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation［J］. Cell, 2016,167（1）:187⁃202.e17. doi: 10.1016/j.cell.2016.09.001.
|
