关键词: 点阵双极射频, 皮肤衰老, 治疗结果

Abstract: Guo Lifang, Lin Tong, Huang Yuqing, Liu Yuzhen. Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China Corresponding author: Lin Tong, Email: ddlin@hotmail.com 【Abstract】 Objective To evaluate the clinical efficacy and safety of a fractional bipolar radiofrequency device for the treatment of wrinkles of the face and neck. Methods This study enrolled 39 volunteers （including 37 females and 2 males aged 35 － 60 years） with Fitzpatrick skin type IV － V and Fitzpatrick wrinkle scale score of 4 － 6. All the subjects received three sessions of treatment with a fractional bipolar radiofrequency device at intervals of 4 － 6 weeks. Follow-up visits were scheduled at one month after each treatment session for evaluation of efficacy （using standardized photography）, subjective satisfaction and adverse effects. Results After three sessions of treatment, all the subjects experienced a significant decrease in Fitzpatrick wrinkle scale compared with baseline values, and wrinkle improvement score increased with the increase in treatment sessions. The Fitzpatrick wrinkle scale score for forehead wrinkles, glabella wrinkles, fishtail lines and neck wrinkles in these subjects after three sessions of treatment significantly differed from that before treatment （all P < 0.01）. Significant differences were also observed in the wrinkle improvement score for forehead wrinkles between these subjects after two sessions and one session of treatment （P < 0.01）, and observed in that for glabella wrinkles, fishtail lines and neck wrinkles between these subjects after three sessions and one session of treatment （P < 0.05 or 0.01）. Side effects were mild with no significant downtime. Conclusion Fractional bipolar radiofrequency may be a safe and effective option for the treatment of wrinkles of the face and neck in individuals with Fitzpatrick skin type IV － V.

Key words: Fractional bipolar radiofrequency, Skin aging, Treatment outcome