中华皮肤科杂志 ›› 1991, Vol. 24 ›› Issue (6): 363-365.

• 论著 •    下一篇

寻常痤疮患者与正常人皮脂溢出率和痤疮丙酸杆菌计数的对比研究

周华, 沈永年, 吴绍熙   

  1. 中国医学科学院皮肤病研究所
  • 收稿日期:1990-07-12 修回日期:1990-11-24 出版日期:1991-12-15 发布日期:1991-12-15

Cornparative Studies of Sebum Excretion Rate and Propionibacterium Acnes Counts in Acne Vulgaris Patients and in Normal Control Subjects

ZHOU Hua, SHEN Yong-Nian   

  1. Institute of Dermatology, Chinese Academy Madical Sciences, Nanjing
  • Received:1990-07-12 Revised:1990-11-24 Online:1991-12-15 Published:1991-12-15

PDF (PC)

264

赞

摘要： 采用皮脂重量直接侧定公测定皮脂溢出率(SER),采用皮肤擦洗取菌法测定痤疮丙酸杆菌数(PAC)、对12例炎症性寻常痤疮患者和12例年龄性别配对的正常人前额皮肤的PAC和SER进行了定量对比研究,发现寻常痤疮患者组PAC(几何均数4463个/cm2)明显高于正常人组(几何均数1662个//cm2),但痤疮病情轻重和PAC高低无关.痤疮患者SER亦明显高于配对正常人,并且AER的高低和病情程度相平行.结果提示:皮脂产生增加是痤疮重要发病因素之一,而痤疮丙酸杆菌在痤疮的发生和炎症的产生中仅起间接作用.

关键词: 白癜风, 甲状腺球蛋白抗体, 甲状腺过氧化物酶抗体, 自身免疫甲状腺病

Abstract: Sebum Excretion Rate(SER) measured by direct gravimctric method and Propionibacterium Acncs Counts(PAC) by detergent scrub technique were studied nn the forehead in twelve patients with inflammatory acne vulgaris and in twelve age and sex matched control subjects.It was found that all patients with acne had higher SER than those of control subjects and the clinical severity of acne was directly correlated to the SERAlthough the PAC in acne group(geometric mean 44668CFU/cm2 was also noted to be higher than those of the control group(gevmetric mean 1622CFU/cm2),the correlation between PAG and the scverity of acne was not obtained.These results suggest That a higher schum production is one of the inzportant factors in the pathagcnesis of acne,but Pro-pionibacterium acnes may only be one of the indirect factors troth in the pathogencsis of acne and in the mediation of inflammation.