中华皮肤科杂志 ›› 1989, Vol. 22 ›› Issue (2): 83-85.

• 论著 • 上一篇    下一篇

IIF法对人口腔中念珠菌粘附与增殖状态的研究

吕昭萍, 王正文, 孙穆雍, 甘自俊   

  1. 昆明医学院附一院皮肤科
  • 收稿日期:1987-10-31 修回日期:1988-03-01 出版日期:1989-04-15 发布日期:1989-04-15

STUDY OF THE ADHERENCE AND PROLIFEROUS STATES OF CANDIDA ON HUMAN ORAL EPITHELIUM BY IIF TECHNIQUE

LÜ zhao-Pies, WANG Zheng-Wen   

  1. Kunming Medical College, Yunnan
  • Received:1987-10-31 Revised:1988-03-01 Online:1989-04-15 Published:1989-04-15

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摘要： 本文用IIF法对319份念珠菌带菌者口腔内念珠菌对粘膜上皮细胞的粘附及增殖状态进行了研究.实验显示,正常人及无念珠菌病发病倾向者,口腔内念珠菌多呈单个芽孢粘附于上皮细胞.有念珠菌病发病倾向者,念珠菌多有不同程度增殖.念珠菌对口腔粘膜上皮细胞呈不均等粘附,其菌丝常穿入上皮细胞.IIF法检测念珠菌不仅敏感、快速、特异,且能直接反映其在休内的增殖致病状态.

Abstract: The adherence and proliferous states of 319 Candida specimens from human oral cavity were studied using indirect immuno-flourescent (IIF) technique.The results showed that in healthy persons and the patients with other diseases having no tendency of opportunistic infection there were only single Candida spores adhering to the oral epithelial cells.Them was prominant proliferation of Landida on the oral epithelium in thrush patients arid most of the patients having a tendency of Candida intection.Our experiment showed that the adherence and proliferation of Candida and the penetration of Candida hyphae into oral epithelial cells may be an early sign of Candida infection.IIF technique could directly reflect the pathogenicity of Cmdida.It was also eon;idered to be sensitive,fast and easy to use.