中华皮肤科杂志 ›› 1989, Vol. 22 ›› Issue (2): 78-80.

• 论著 • 上一篇    下一篇

正常人皮肤黑素细胞分布的观察

崔建, 沈丽玉, 王光超   

  1. 北京医科大学第一医院皮肤科
  • 收稿日期:1987-11-24 修回日期:1988-04-04 出版日期:1989-04-15 发布日期:1989-04-15

THE DISTRIBUTION OF MELANOCYTES IN HUMAN SKIN

CUI Jian, SHEN LI-Yu   

  1. The First Hospital of Beijing University, Beijing
  • Received:1987-11-24 Revised:1988-04-04 Online:1989-04-15 Published:1989-04-15

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摘要： 利用表皮分离一多巴染色法对正常人体5个部位的53个皮肤标本表皮黑素细胞进行观察分析,发现黑素细胞存在明显的部位差异,但其数量不随年龄改变.颈、上肢和后背皮肤黑索细胞数量较多(均值分别为1780、1030、 1025/mm2),染色深、有较多短而细的分枝;下肢和胸腹皮肤黑素细胞数量较少(均值分别为784、783/mm2),染色淡、分枝少,但胞体较大、分枝粗沃、有多级分枝.黑素细胞数反的部位差异可能是出生后各部位紫外线照射程度不同、使黑素细胞分裂增殖量不等造成的;其功能活性和形态改变可能受紫外线、表皮黑素单位内角朊细胞的代谢功能、数量及其细胞动力学的影响.

Abstract: Using 2N NaBr skin splitted-dopa stain,we studied the epidermal melanocytes of 53 specimens from five major regions of normal Chinese.Our result confined that there were wide individual and regional variations; but the ntunber of melanocytes,which ranged from 783/mm2 on the chest-abdomen to 1780/mm2 on the neck,was not related to age.The melanocytes on the neck,upper extremity,and back showed stronger dopa reaction and had more thin dendrties; while the melanocytes on the low extremity and chest-abdomen had larger cell body,weaker dopa,reaction,and fewer thick branches wish secondary dendrites.The regional difference of melanocye population were probably due to unequal division and proliferation of mclanocytes which may be affeted by UV radiation after birth.The functional and cytelogic changes of mclanocyte may be influenced by UV,keratinocyte kinetics,and the number of keratinocytes in an epidermal melanin unit.