中华皮肤科杂志 ›› 1984, Vol. 17 ›› Issue (4): 238-240.

• 论著 • 上一篇    下一篇

地方性慢性砷中毒一流行病学与临床表现

新疆医学院, 新疆车排子医院, 新疆流研所, 奎屯市防疫站   

  1. 新疆医学院, 新疆车排子医院, 新疆流研所, 奎屯市防疫站
  • 出版日期:1984-12-15 发布日期:1984-12-15

Endemic arsenism：Epidemiological survey and clinical analysis

Xinjiang Medical College   

  • Online:1984-12-15 Published:1984-12-15

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摘要： 本文报道了新疆某地区2个单位.长期伙用高砷自流井水(含砷量分别为0.48-0.61mg/L,正常允许最高量为0.04mg/L),发生了慢性砷中毒.作者普查了6岁以上居民889人,检出砷中毒病人579人,检出率为65.1%.发病与年龄、饮水年限及饮水含砷量成正比关系,与职业无关.其临床表现主要在皮肤、躯干弥散性棕褐色色素斑,夹杂淡白色斑点为典型的砷色素异常;对称性手足点状或鸡眼状角化为典型的砷角化;多发性癌变常伴发砷角化或砷色素异常为砷癌的特征.作者根据临床表现、皮肤病理改变及实验室测定组织内含砷量提出了地方性慢性砷中毒的诊断标准,并扼要地讨论了砷中毒的发病机理.

Abstract: An out-break of endemic arsenism occurred in certain areas in Xinjiang due to prolonged in take of well-water containing high arsenic content of 0.48-0.61 mg/L (normal permissible content being 0.04mg/L).Among 889 inhabitants with their age above 6 in 2 localities, 579 persons suffered from arsenism with a morbidity of 65.1%.The incidence varies in direct proportion with age: duration of taking well-water and amount of arsenic in well-water.