中华皮肤科杂志 ›› 1991, Vol. 24 ›› Issue (4): 225-227.

• 论著 • 上一篇    下一篇

SLE患者补体的免疫沉淀抑制作用的检测及临床意义

张晓惠1, 许德清2, 王莲芳3   

  1. 1. 中山医科大学孙逸仙纪念医院皮肤科, 广州, 510120;
    2. 指导者;
    3. 中国人民解放军第一五七医院
  • 收稿日期:1989-12-24 修回日期:1990-06-15 出版日期:1991-08-15 发布日期:1991-08-15

Detection of inhibition of immune precipitation by complament and its clinical significance in SLE patients

ZHANG Xiao-Hui1, XU De-Qing2   

  1. Sun Yat-Sen Medical Hospital,Sun Yat-Se Medical University, Guangzhou
  • Received:1989-12-24 Revised:1990-06-15 Online:1991-08-15 Published:1991-08-15

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摘要： 采用放免法测定补体的免疫沉淀抑制作用(IIPC),共测102份正常人血清和93份SLE血清,正常下限为84%.63.4%SLE患者IIPC低于84%.病情越重.IIPC越低,同时伴有CH50, C3及C4含量降低,抗DNA抗体增加,能更敏感地反映SLE病情.

Abstract: inhibition of immune precipitation by complament (IIPC) was measured by radioimmunoassay in 102 normal human sera and 93 SLE patients' sera. The low limit value of IIPC in the normal control was 84%. IIPC levels of sera in 63.4 percent of SLE patients were less than 84%. The mare serious the SLE patients' condition was, the lower IIPC value was. Sera with low concentrations of CH50, C3, and C4 and with high titer of anti-DNA antibody showed reduced IIPC levels.The IIPC level of serum can reflect SLE activity more sensitively.