中华皮肤科杂志 ›› 1990, Vol. 23 ›› Issue (5): 319-321.

• 论著 • 上一篇    下一篇

青篙琥酯和反应停对小鼠光变态反应的影响

张书岭1, 高玉祥2, 高人燕2   

  1. 1. 河南省人民医院;
    2. 蚌埠医学院皮肤病学教研室
  • 收稿日期:1988-12-30 修回日期:1989-08-02 发布日期:1990-10-15

The effect of artesunatc ana thalidomide on photoallergy

ZHANG Shu-Ling1, GAO Yu-Xiang2   

  1. 1. Henan People's Hospital;
    2. Bengbo Medical College, Anhui
  • Received:1988-12-30 Revised:1989-08-02 Published:1990-10-15

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摘要： 本文分别以盐酸氯丙嗪和氨苯磺胺为致光敏剂,加用UVA及UVB-UVA照射,在小鼠体内成功地建立了接触性光变态反应(CPA)及全身性光变态反应(SPA)模型,并对青简瑰醋和反应停的抗光变态反应作用进行了观察,证明该两种药物对CPA和SPA邻分别有显著的抑制作用.

Abstract: We have successfully induced contact pho- toallergy (GPA) and systemic phntoallergy (SPA) in mice to chlorphromazine-UVA and aulfanilamide-UBV-UVA, and using these models, we demonstrated that artesunate and thalidomide both can significantly inhibit the reactions of CPA and SPA.