中华皮肤科杂志 ›› 1989, Vol. 22 ›› Issue (5): 304-305.

• 论著 • 上一篇    下一篇

毛囊在白癫风恢复中的作用

崔建, 沈丽玉, 王光超, 王书合   

  1. 北京医科大学第一医院
  • 收稿日期:1988-03-14 修回日期:1988-06-19 出版日期:1989-10-15 发布日期:1989-10-15

role of hair follicle in repigmentaticn of vitiligo

CUI Jian, SHEN Li-Yu   

  1. The First Hospital of Beijing Medical University
  • Received:1988-03-14 Revised:1988-06-19 Online:1989-10-15 Published:1989-10-15

摘要: 我们利用扫描电镜观察白斑酊治疗前后白癫风皮损和正常皮肤内毛囊,发现白癫风皮损内毛囊外根鞘细胞表面无黑素细胞存在,正常皮肤也只有生长期毛囊的漏斗部有散在儿个黑素细胞,而白癫风色素恢复期皮肤内各期毛囊的表面可见大量黑素细胞,从而证明毛囊为白癫风色素恢复时黑素细胞的来源地,其中,下部位外毛根鞘内可能存在着黑素细胞库.

Abstract: We used scanning electron microscopy to study the hair follicles in normal skin, vitiliginous lesion and repigmented skin. There were few melanocytes in the infundibulum of some anagen follicles in normal skin. In the hair follicles of vitiliginous lesions, there were no melanocytes found in the outer root aheath. But in the repigmented area, there were a lot of melanocytes along the surface of the outer root sheath at any hair growing stages. Our observation proposed another evidence that the "melanocyte reservior" may exist in the middle and lower protion of the hair follicle, from there the melanocytesl migrate upward during the period of repigmentation.