中华皮肤科杂志 ›› 2025, Vol. 58 ›› Issue (8): 699-708.doi: 10.35541/cjd.20250080

• 指南与共识·结缔组织病 • 上一篇    下一篇

[开放获取]    局限性硬皮病诊疗专家共识(2025版)

中华医学会皮肤性病学分会    中国医师协会皮肤科医师分会   

  1. 中华医学会皮肤性病学分会    中国医师协会皮肤科医师分会
  • 收稿日期:2025-02-19 修回日期:2025-06-17 发布日期:2025-08-05
  • 通讯作者: 肖嵘;高兴华;陆前进 E-mail:xiaorong65@csu.edu.cn; gaobarry@hotmail.com; qianlu5860@pumcderm.cams.cn
  • 基金资助:
    国家自然科学基金(82373486、82203930、82203932、82304024)

Expert consensus on the diagnosis and treatment of localized scleroderma (2025 edition)

Chinese Society of Dermatology; China Dermatologist Association   

  1. Chinese Society of Dermatology; China Dermatologist Association
  • Received:2025-02-19 Revised:2025-06-17 Published:2025-08-05
  • Contact: Xiao Rong; Gao Xinghua; Lu Qianjin E-mail:xiaorong65@csu.edu.cn; gaobarry@hotmail.com; qianlu5860@pumcderm.cams.cn
  • Supported by:
    National Natural Science Foundation of China(82373486、82203930、82203932、82304024)

摘要: 【摘要】 局限性硬皮病(LS)是一种以真皮及皮下组织纤维化为主要特征的罕见皮肤病,严重者可影响患者容貌、皮肤功能及生活质量。目前国内缺乏LS的相关诊治指南或共识,临床上该病的诊断与治疗缺乏一定的规范性。为提升我国皮肤科临床医生对LS的认识,规范诊治行为,中华医学会皮肤性病学分会、中国医师协会皮肤科医师分会组织国内皮肤病学领域的权威专家,通过系统检索文献,结合国内外研究现状与进展,对LS临床分型、诊断和鉴别诊断、评估方法、治疗方案等进行系统梳理与总结,达成共识,以期为该病规范化诊疗提供指导意见。

关键词: 硬皮病, 局部性, 硬斑病, 诊断, 治疗, 专家共识

Abstract: 【Abstract】 Localized scleroderma (LS) is a rare skin disorder characterized by fibrosis in the dermis and subcutaneous tissues. In severe cases, it can affect patients′ appearance, physical function, and quality of life. Currently, there is a lack of Chinese guidelines or consensus on the diagnosis and treatment of LS, leading to variability in clinical practice. To enhance dermatologists′ understanding of LS and standardize its diagnosis and management, the Chinese Society of Dermatology and the China Dermatologist Association organized a panel of leading experts in the field of dermatology to develop a consensus through systematic literature review and integration of recent Chinese and international research advances. The consensus comprehensively summarized the clinical subtypes, diagnostic criteria, differential diagnoses, and assessment methods of LS, as well as treatment strategies for LS, aiming to provide evidence-based guidance for standardizing the clinical management of LS in China.

Key words: Scleroderma, localized, Morphea, Diagnosis, Treatment, Expert consensus

引用本文

中华医学会皮肤性病学分会 中国医师协会皮肤科医师分会. [开放获取]    局限性硬皮病诊疗专家共识(2025版)[J]. 中华皮肤科杂志, 2025,58(8):699-708. doi:10.35541/cjd.20250080

Chinese Society of Dermatology, China Dermatologist Association. Expert consensus on the diagnosis and treatment of localized scleroderma (2025 edition)[J]. Chinese Journal of Dermatology, 2025, 58(8): 699-708.doi:10.35541/cjd.20250080